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Gastrointestinal effects are particularly common, especially during treatment initiation and dose escalation: Nausea classified as 'very common' (affecting more than 1 in 10 patients) in the SmPC [1] [2] Vomiting 'common' (affecting up to 1 in 10 patients) Diarrhoea 'common' according to the MHRA/EMC SmPC Constipation 'common', likely related to delayed gastric emptying Abdominal pain or discomfort 'common', generally mild to moderate in severity Decreased appetite 'common', which may lead to reduced food intake and weight loss (note that while weight loss can occur with Ozempic, it is not licensed for weight management in the UK) [1] [2] These gastrointestinal symptoms usually diminish over time as the body adapts to the medication

Whilst mild bloating is relatively common during GLP-1 therapy and often resolves with time and dietary adjustments, certain symptoms warrant prompt medical evaluation

Conflicts of interest disclosure The author declares there is no conflict of interest to declare

"Our program has never been about the medications alone

It should be part of a wider weight management plan that includes healthy eating and regular physical activity

Mild nausea or reduced appetite for certain foods does not prevent weight loss