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In this Review, Moheet and colleagues describe these conditions, with particular emphasis on the effects of CFTR modulator therapy, as well as the challenges related to ageing in people with cystic fibrosis.

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Moreover, in-vivo studies revealed an increase in the peak plasma concentration (Cmax), area under the plasma concentration-time curve (AUC0-24h) and reduction in time to reach the peak plasma concentration (Tmax) after an oral administration of LPC-3

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