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(6) There are analyses indicating that more than half of all arthroplasty patients are obese, with one large retrospective cohort of 8.3 million individuals reporting that 64% of primary total knee arthroplasty (TKA) patients and 49% of primary total hip arthroplasty (THA) patients are obese

Finally, GLP-1RAs decrease ROS to ease oxidative stress and shield mitochondria (94)

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Mazdutide , cagrilintide , and orforglipron (an oral GLP-1 agonist) represent additional next-generation options that could offer different benefit-risk profiles for endometriosis patients

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6 CT-868, an investigational, once-daily, subcutaneously injected dual GLP-1/GIP receptor agonist currently in Phase II with the potential to be a first in class treatment for glycaemic control as an adjunct to insulin in patients living with type 1 diabetes