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Clinical Trials and Promising Results Multiple clinical trials are underway, with early clinical trials producing exciting data

Diabetes Obes Metab 4:424427 Beysen C, Murphy EJ, Deines K et al (2012) Effect of bile acid sequestrants on glucose metabolism, hepatic de novo lipogenesis, and cholesterol and bile acid kinetics in type 2 diabetes: a randomised controlled study

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Phase 2 trial data (NEJM, 2023) showed substantial MRI-PDFF-measured liver fat reductions at 8 mg and 12 mg weekly doses, with some participants falling below the 5% hepatic steatosis threshold