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Activation of TGR5 by BA in brown adipose tissue and muscle increases energy expenditure and reduces diet-induced obesity (81)
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0.79) Heart failure (HR 0.62
It minimizes the action of the GLP-1 hormone, which controls appetite and insulin secretion
But in that same study, people taking the pill were more likely to report side effects and discontinue treatment than those taking injections (Journal of Pharmacy Technology, 2024)
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