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Elevated 2-AG is known to normalize hyperactivation in stress-related brain regions

Online products marketed as research only do not provide the same protections

Some studies say that as much as half of the weight you lose comes from the loss of lean muscle

In contrast, in human clinical trials with semaglutide or tirzepatide, about 60% of patients achieve a 20% reduction in weight and can keep that weight off with continued use

To minimise the risk of GI AEs, patients should be advised to reduce portion sizes and to reduce the fat content of their meals

Use of the injections started increasing in 2022, followed by "a sharp increase" in 2024
