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Persistent vomiting or diarrhea : Seek urgent care if unable to maintain hydration or if severe gastrointestinal symptoms persist for more than 24 hours

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Participants (18 years) with inadequately controlled type 2 diabetes (HbA1c 80-100%) with metformin and with or without sulfonylurea were randomly assigned (1:1) by an interactive web-response system to 20 mg or 10 mg once-weekly semaglutide

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