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Id also raise the question of whether the incretins and other GLP-1 agonists will ever be free of adverse GI symptoms, as it seems intrinsic to the drugs mechanism.

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Learn the common causes of rectal bleeding, from hemorrhoids to serious conditions

Doctors prescribe this drug for blood sugar control when diet, exercise, or metformin are not enough, or as a first-line therapy under new medical guidelines.

All of these unanswered questions only add to the urgency of determining who is most likely to benefit from GLP-1s. : Luliia Burmistrova / Getty

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