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Cardiovascular Effects Dose-dependent increases in heart rate were observed with retatrutide: Heart rate increases peaked at approximately 24 weeks Gradually declined thereafter while remaining elevated above baseline This pattern is similar to that observed with other GLP-1 receptor agonists[4] The clinical significance of these heart rate changes requires further evaluation in larger and longer-term studies

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The prevalence of obesity has increased worldwide over the past three decades

Food and Drug Administration Adverse Event Reporting System (FAERS) database has revealed that glucagon-like peptide 1 receptor agonists (GLP-1RAs) do not appear to...

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Accordingly, the number of patients suffering from dumping syndrome has increased