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The Pathophysiological Associations Between Obesity, NAFLD, and Atherosclerotic Cardiovascular Diseases

This strongly suggests that stepwise administration should be effective at breaking the weight-loss plateau commonly observed with monotherapies

GLP #2 has also demonstrated success over the long term

10.1172/JCI119833 [DOI] [PMC free article] [PubMed] [Google Scholar] 177.Chinda K, Palee S, Surinkaew S, Phornphutkul M, Chattipakorn S, Chattipakorn N

Similarly, the plasma concentration data for mice were transferred from Watson LIMS through a validated electronic interface to Phoenix WinNonlin version 8.1 (Certara L.P., Princeton, NJ, USA) for PK evaluation

While previous research primarily focused on T2D or obesity-specific populations, our study specifically examines therapeutic implications for MASLD patients, addressing a critical knowledge gap regarding the benefits of combination therapy on various clinical endpoints including all-cause hospitalization, all-cause mortality, MAKE, and MALO in this population