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Initially designed for managing type 2 diabetes, these GLP-1 receptor agonists have proven so effective at curbing appetite that theyre now being prescribed off-label for weight loss

Herein, we show that broad-spectrum antibiotic cocktail (ABX)-treated mice displayed hypolocomotion and elevated levels of the gut hormone glucagon-like peptide-1 (GLP-1)

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This amount of weight loss has not been accomplished before with medical therapy