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What You Can Do Now to Prepare Even if your goal is to eventually use retatrutide, there is no reason to delay taking action on your weight loss and metabolic health: Start with a proven medication

This gradual approach helps manage adverse events and makes it easier for patients to stay on the medication long term

As for safety, the mid-stage trial found Ziihera to be well-tolerated, with only two patients discontinuing treatment due to toxicities

These mechanisms contribute to improved glycemic control and significant weight loss in appropriate patient populations

Nausea is often considered a significant side effect of Ozempic