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Consider using a 'pinch-up' technique if you have very little subcutaneous fat

GLP-1R activation has a significant effect on glycemic control in patients with T2DM through a variety of mechanisms, including stimulation of insulin secretion, inhibition of glucagon secretion, protection of -cells from apoptosis, slowing gastric emptying and increasing satiety ( 2 GLP-1R GLP-1R is a G protein-coupled receptor (Wu et al., 2020) (Figure 1A)

The honest answer is that it depends entirely on your individual risk factors, priorities, and health history

10.1038/nature22394

Smith, 2023)
