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Reduced caloric intake and digestion One reason Mounjaro may increase feelings of cold is due to reduced food intake, which affects body heat production

Very high-fat foods take more time to digest and sit in the stomach for longer

Mounjaro (tirzepatide) Summary of Product Characteristics

A patient on Ozempic 2 mg switching to Mounjaro typically starts at Mounjaro 2.5 mg and works up

In a systematic review, three-component Major Adverse Cardiovascular Events (3-p MACE) was reduced, with an HR of 0.86 (95% CI 0.800.92) for those over 65 years old, and there was an even more pronounced effect in those over age 75 (HR 0.75, 95% CI 0.610.92) (120)

Its important to follow your doctors advice while using it