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The LactMed database explicitly warns that some brands of oral semaglutide contain the absorption enhancer salcaprozate sodium, which may enter milk and accumulate in infants

Animal studies demonstrate that GLP-1 receptor agonists reduce dopamine signaling in this pathway

On average, volunteers in the retatrutide clinical trial who received the study drug rather than a placebo lost an average of 70.3 pounds over about a year-and-a-half, with more than 45% of participants losing more than 30% of their body weight