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Fig.6 WuXi Biology Liver Disease Models References Abdelmalek M F, Harrison S A, Sanyal A J
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Here are the main mechanisms: They boost insulin secretion after meals (but in a glucosedependent way, meaning they act more when blood sugar is higher)

Most of this comes from reduced caloric intake rather than dramatic metabolic shifts, though visceral fat mobilization has already begun at the cellular level

CCK producing neurons are known to be important for appetite control

Adults aged 18 years with diabetes prescribed biguanides were included
