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General Eligibility Criteria: Based on published clinical guidelines, GLP-1 medications for weight management are typically considered for adults with BMI of 30 or higher, or BMI of 27 or higher with at least one weight-related condition such as hypertension, hyperlipidemia, type 2 diabetes, or pre-diabetes

Adequately powered trials with long-term follow-up focusing on T2D prevention as a primary outcome in youth are required

Whilst their primary indication remains glycaemic control, emerging evidence suggests GLP-1 receptor agonists exert effects beyond glucose metabolism

It signals satiety to your brain, reducing appetite