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That decision requires medical history, contraindications, current medications, goals, and physician review

Sources Mounjaro KwikPen 10mg solution for injection in pre-filled pen, emc [accessed 16 October 2025] Obesity, NHS [accessed 16 October 2025] Once-Weekly Semaglutide in Adults with Overweight or Obesity, NEJM [accessed 16 October 2025] Tirzepatide Once Weekly for the Treatment of Obesity, NEJM [accessed 16 October 2025] Wegovy 0.25 mg, FlexTouch solution for injection in pre-filled pen, emc [accessed 16 October 2025] Patient Reviews Related Weight Loss Treatments Further Reading on Weight Loss Do Appetite Suppressants Work

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The length of each intervention consisted of an 11-week drug titration period as per its monograph, which was followed by 4 weeks of AID use for the primary outcome assessment

For the analysis involving patients with both T2DM and obesity, we included those who were prescribed GLP-1RAs or control medications within one year following their diagnosis of both T2DM and obesity, between April 2013 and April 2019

The drug also improved cardiac risk factors such as non-HDL cholesterol levels, waist circumference and blood pressure, she added
