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[DOI] [PubMed] [Google Scholar] 170.Nian M, Drucker DJ, Irwin D

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The LIVE trial in patients with heart failure with reduced ejection fraction (HFrEF) showed no improvement in left ventricular (LV) systolic function

While for understanding disease mechanisms and testing therapies, the valuable animal models have limitations in their ability to fully replicate human conditions due to species differences