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Double-blind, randomized clinical trial comparing the efficacy and safety of continuing or discontinuing the dipeptidyl peptidase-4 inhibitor sitagliptin when initiating insulin glargine therapy in patients with type 2 diabetes: the CompoSIT-I Study

Severe nausea, vomiting, or diarrhoea on Mounjaro can lead to dehydration, which puts extra strain on the kidneys

The form notes that initial approval is limited to 12 months

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Mambelli-Lisboa, N

Conversely, intestinal proglucagon gene expression is reduced during fasting and stimulated upon food consumption
