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[5] Its also important to note that the best weight loss results from either medication are gained by combining your treatment plan with sustainable, long-term lifestyle changes, including a reduced-calorie diet and increased physical activity

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Yellow flags worth discussing at your next appointment These are not emergencies but deserve conversation with your prescriber

The addition of glucagon receptor agonism raises theoretical considerations around heart rate elevation , and Phase 2 data did show modest increases in resting heart rate in some participants a finding that will require careful monitoring in Phase 3 cardiovascular outcome trials

Other Diabetes Medications in Pregnancy If you need diabetes management during pregnancy, medications considered safer include insulin (first-line, safest option), metformin (used by some providers though technically off-label), and glyburide (sometimes used for gestational diabetes)

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