are there any natural glp-1 agonists receptor and next-generation metabolic hormone therapies in chronic kidney disease npj Metabolic Health and Disease

I was on Zepbound for one year

B.MunteanuM.DotsenkoS.NiemoellerE.BokaG.WuY.et al (2014)

Contrariwise, in the study by Jensterle et al

Liraglutide and semaglutide are GLP-1 RAs whereas tirzepatide is a combined agonist to both GLP-1 and GIP (glucose-dependent insulinotropic polypeptide) receptors

A systematic review and meta-analysis of supervised-exercise training interventions in children and adolescents showed that both aerobic and resistance exercise, at vigorous or moderate-to-vigorous intensities, with a volume of 60 min/session and a frequency of 3 sessions/week, aiming to improve cardiorespiratory fitness and muscular strength had benefits on hepatic fat content reduction in youth [122]

Researchers who are responding well to tirzepatide, losing weight consistently, and tolerating the medication, should seriously consider staying the course