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When considering GLP-1 receptor agonists for patients with fatty liver disease, several factors influence the choice of agent, though direct head-to-head comparisons specifically in NAFLD populations are limited

doi: 10.1016/j.heliyon.2023.e19463

Learn more Further Reading What Is Retatrutide: Mechanism, Trial Data, and Candidacy Deep-dive on the triple-agonist receptor biology, phase 2 and phase 3 trial results, who is a clinical candidate, and what monitoring is required

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GIP (glucose dependent insulinotropic polypeptide) receptor Enhances insulin response after meals, has direct effects on adipose tissue, and works synergistically with GLP-1 to amplify metabolic signaling

2012, Nandy et al