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It means the current products have not been demonstrated to work

Phase 3 TRIUMPH trial results The Phase 3 TRIUMPH-4 trial, announced in late 2025, confirmed and even improved on the Phase 2 numbers

This is the section that gets glossed over most often, and its the one most worth understanding

The sound may be simple, as in a single tone, or complex, including multiple tones, and can change markedly from moment to moment

Luo M, et al

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