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doi: 10.1016/S1474-4422(20)30173-3 [DOI] [PubMed] [Google Scholar] 169.Detka J, Gombik K

Unfortunately, rapid weight loss can stress the body and disrupt the normal hair cycle, causing shedding. Nutritional deficiencies and hormonal shifts common during medical weight loss may worsen this effect

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Retatrutide activates three metabolic pathways, while semaglutide activates one

Small, controlled weight loss may be acceptable in select patients

Differential gene expression of myocytes from semaglutide-treated animals highlighted a broad increase in metabolism, including BCAA catabolism, fatty acid metabolism, the tricarboxylic acid (TCA) cycle, and glycolysis ( Figure 3C )