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Gonzalez, M

The participants in the highest loop diuretic dose category lost 6.9% of their body weight on average

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The following PD measurements were included in this study as exploratory endpoints: changes from baseline in lipid profiles, meal intake, patient-reported appetite sensation, body weight, FPG, HbA1c, 7-point self-monitored blood glucose (7-point SMBG), and immunogenicity assessments

Monitoring schedules vary by medication: for example, naltrexone/bupropion (Mysimba) requires blood pressure and heart rate monitoring before treatment, during dose escalation, and regularly thereafter