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The high dose of cyanocobalamin is generally well-tolerated due to the vitamins water-soluble nature and efficient excretion of excess amounts
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McEvoy RD, Antic NA, Heeley E, et al
In a comprehensive US administrative database from 2005 to 2008, GLP-1-based treatments, particularly sitagliptin and exenatide, were associated with a significantly increased risk of acute pancreatitis-related hospitalization in adults with T2DM [59], thereby reinforcing prior mechanistic experimental studies and spontaneous reports to the FDA suggesting a potential causal relationship
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