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After 56 weeks: Placebo group lost 1.6% of body weight Starting dose (3.75/23 mg) group lost 5.1% of body weight Top dose (15/92 mg) group lost 10.9% of body weight Beyond weight loss, the CONQUER trial showed significant improvements in blood pressure, waist circumference, lipid profiles, glycemic parameters, and inflammatory biomarkers compared to placebo

Unlike GLP-1 and GLP-2, which have well-established functions and clinical applications, GLP-3 remains somewhat enigmatic in the scientific community

"We don't know what is actually in there, let alone if it is the drug and then how it was made

Semaglutide is not appropriate for patients with a history of medullary thyroid cancer, family history of MEN 2 syndrome, severe gastroparesis, or severe inflammatory bowel disease

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