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Long-term semaglutide responders continue losing weight steadily through month six and beyond, with total losses often reaching 15 to 30 percent of body weight by six months in clinical trials

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Other common side effects of semaglutide drugs include stomach pain, diarrhea, and constipation

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Common gastrointestinal adverse effects reported with Wegovy include: Nausea (affecting approximately 44% of patients) Vomiting (approximately 24%) Dyspepsia (indigestion) Abdominal pain Constipation These symptoms typically occur during dose escalation and often improve over time as the body adjusts to the medication