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FDA approval is anticipated in 2026, through the FDA's national priority voucher program, positioning Lilly to compete aggressively in the oral segment
It is currently one of the most studied next-generation peptides in metabolic research
Clinical Perspective The panel concluded that the benefits of GLP-1RAs far outweigh potential ocular risks, given their proven: ~11.5 % HbA1c reduction 515 % weight loss (SURPASS & STEP programs) ~1426 % relative risk reduction in major CV events Hence, appropriate screening, not avoidance, should guide practice
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The obesity and type 2 diabetes mellitus epidemics have prompted expanded use of incretin-based therapies
