glp-1 side effects pancreatitis Ozempic and Drugs: Risk of Severe GLP-1RA Essentials in Gastroenterology: Side

The drugs of interest included FDA-approved GLP-1RAs [26]: semaglutide, liraglutide, dulaglutide, exenatide, lixisenatide, and albiglutide

These studies uniformly showed that Liraglutide significantly reduced body weight when used as an adjunct therapy with diet and exercise

[DOI] [PMC free article] [PubMed] [Google Scholar] [148].Yu Pan C, Han P, Liu X, Yan S, Feng P, Zhou Z, Lv X, Tian H, Jin Kui Y, Su B, Shang S, Niemoeller E, Lixisenatide treatment improves glycaemic control in Asian patients with type 2 diabetes mellitus inadequately controlled on metformin with or without sulfonylurea: a randomized, double-blind, placebo-controlled, 24-week trial (GetGoal-M-Asia), Diabetes/metabolism research and reviews, 30 (2014) 726735

Kaplan-Meier curves demonstrating lower cumulative incidence of overall cancer among GLP-1RA initiators (blue line) compared with matched nonusers (orange line) during up to 8 years of follow-up

Regular follow-up during treatment is also crucial for monitoring any adverse effects and adjusting the regimen as needed

Rare side effects include gallbladder disease, pancreatitis, acute kidney injury (typically related to hypovolemia), hypersensitivity reactions, and gastroparesis [39,40]