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Clinicians must carefully evaluate individual patient risk factors, particularly personal or family history of MTC or multiple endocrine neoplasia syndrome type 2 (MEN 2), before prescribing these agents

For weight management, NICE provides guidance on eligibility for specialist weight management services, which may include other pharmacological options such as orlistat (though this can also cause gastrointestinal side effects that may be problematic in IBD)

39 Conventional risk factors for diabetic gastroparesis include a long duration of diabetes, presence of other microvascular complications, smoking, obesity and female sex
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[DOI] [PubMed] [Google Scholar] 90.Dei Cas A., Micheli M.M., Aldigeri R., Gardini S., Ferrari-Pellegrini F., Perini M., Messa G., Antonini M., Spigoni V., Cinquegrani G., et al

In this article, the term refers to dosing strategies below the initiation levels used in large clinical trials (see Key Definitions below)
