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Glucagon is known to influence gut motility, and it is plausible that stimulating these receptors may contribute to altered bowel function

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10 Pharmacists who are aware of cases of exenatide-associated acute pancreatitis or other serious adverse drug reactions are encouraged to report their findings to MedWatch, the FDAs adverse drug reporting program (www.fda.gov/Safety/MedWatch/ Anti-exenatide Antibodies: In phase III clinical trials, 41% to 49% of patients receiving exenatide developed anti-exenatide antibodies

This suggests that GLP-1 may have cardiovascular protective properties

This is where many patients get lost

10.1186/s12933-017-0646-z 48 LeporeJ