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One particular retrospective study reported that the discontinuation of endoscopy occurred in less than 1% of procedures, yet was twice as common among GLP-1 RA users (Alkabbani et al
60 When gallstones obstruct the cystic duct, bile flow is impeded, resulting in bile stasis and increased pressure within the gallbladder
This is likely due to the combination of dehydration and decreased nutrient intake
GLP-1 medications are powerful tools for weight loss but reduced appetite means reduced nutrient intake, and that creates real risks: muscle loss, micronutrient deficiency, hair thinning, and digestive disruption
Why are GLP-1 agonists contraindicated in specific populations, such as pregnant individuals or those with severe gastrointestinal disorders, and what alternative treatment approaches could providers consider in these cases
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Treatment with GLP-1 RAs was not associated with progression to PDR (1121 of 32 695 [3.4%] vs 1039 of 32 695 [3.2%] events
