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The most recently approved FDA medication for the treatment of obesity, tirzepatide, exerts its physiologic effects as a dual GLP-1R and Gastric Inhibitory Polypeptide Receptor (GIP-R) agonist with better efficacy than the standalone GIP-R agonist semaglutide [39]

Mogollon stresses these medications should be used with caution in patients with gastroparesis

[DOI] [PubMed] [Google Scholar] 4.Banting FG Early Work on Insulin

Tirzepatide should only be used under the guidance of a qualified healthcare provider as part of a complete approach to weight management

This inflammation exacerbates neuronal injury and promotes further A and tau pathology

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