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These neurons integrate peripheral metabolic cues via vagal afferents and project directly to the VTA and NAc, where GLP-1R activation decreases food intake and body weight, particularly suppressing consumption of highly palatable foods [12,21]

Yes , and this is closely related to the widely discussed phenomenon known as Ozempic Face. Ozempic Face describes the gaunt, hollow, or prematurely aged facial appearance that can follow rapid, significant weight loss on GLP-1 medications

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In rodents, non-shivering thermogenesis is mediated by the uncoupling protein-1 (UCP-1) in brown adipose tissue (51)

Always verify your concentration before calculating anything