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Peptide-Drug Conjugates (PDCs) PDCs combine targeting peptides with cytotoxic payloads to deliver drugs specifically to diseased cells, occupying a niche between small molecules and antibody-drug conjugates

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consequently, the discussion herein will be broad rather than exhaustive

Modulation of blood glucose by melatonin: a direct action on melatonin receptors in mouse hepatocytes

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However, lack of long-term adherence to lifestyle modifications and adverse side effects, poor bioavailability, rapid clearance, and instability of many approved medicines make obesity and diabetes management challenging