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injections of 200 nmol kg 1 MK-801 (n = 8 mice and n = 4 cages), 600 nmol kg 1 MK-801 (n = 7 mice and n = 4 cages) or vehicle (isotonic saline, n = 7 mice and n = 4 cages) for 7 days

Always work under sterile conditions and use a new syringe for each application

It tends to worsen as doses increase and often peaks in the 24 to 48 hours after injection

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