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A: GLP-1 therapy is typically administered as a simple, once-weekly or daily subcutaneous injection

Normally, myocardial energy metabolism relies mainly on fatty acids (70%), with glucose, ketone bodies, and lactate as supplementary sources

They were then placed under anesthesia using isoflurane (4% for induction and 2% for maintenance)

Weight management itself influences GLP-1 function

Many clinicians now prescribe GLP-1 therapies earlier in treatment algorithms, especially for patients with obesity, cardiovascular disease, or high cardiometabolic risk

Hypertension (2015) 65(6):133140.10.1161/HYPERTENSIONAHA.115.05315 163 DaveyKJCotterPDOSullivanOCrispieFDinanTGCryanJFet alAntipsychotics and the gut microbiome: olanzapine-induced metabolic dysfunction is attenuated by antibiotic administration in the rat