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Secondary endpoints included the rate of patients with a weight loss of 10%, monthly headache days (MHD), the rate of patients with a 30% and 50% reduction in MHD, visual outcome parameters, and adverse events (AEs)
Zepbound was approved by the Food and Drug Administration in November 2023 for weight loss in adults with obesity or who are overweight with at least one related condition like type 2 diabetes, high cholesterol, or high blood pressure)

Klausen, M

Insulin plays a permissive role for the vasoactive effect of GIP regulating adipose tissue metabolism in humans
