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Our findings revealed EC 50 values of 3.97 nM and 2.43 nM for GLP-1R internalization mediated by GEP44 and Ex-4, respectively, and EC 50 s of 1.59 nM and 7.13 nM for GEP44 and Ex-4, respectively, for -arrestin-2 recruitment

[DOI] [PMC free article] [PubMed] [Google Scholar] 120.Kanoski S.E., et al

therefore, for this reason it was not used as a target for diabetic therapy, unlike GLP-1

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