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Fourthly, lifestyle factors, such as diet, physical activity, smoking or other possible confounding risk factors affecting metabolism and fat accumulation, were not recorded in this study

Cagrilintide should be provided as the base form or clearly labeled if provided as a salt (acetate, sodium)

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The effect of GLP-1RA on the eGFR-related endpoint worsening kidney function was neutral in the main analysis (HR 0.86, 95% CI 0.721.02), while a statistically significant benefit was detected in the sensitivity analysis excluding ELIXA (HR 0.82, 95% CI 0.690.98) [11]

Specifically, choice sets comparing orally administered semaglutide and liraglutide used PIONEER 9 data only, and choice sets comparing orally administered semaglutide and dulaglutide used PIONEER 10 data only