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This finding could be the result of a lack of a causal role of these tested strains in the metabolic syndrome, reduced viability upon passage through the stomach [212, 213], inadequate dosages, or a lack of engraftment when introduced in the human gut [214]

[DOI] [PMC free article] [PubMed] [Google Scholar] 221.Hostetter TH

Degradation can occur even within the recommended storage window if the cold chain has been broken, the vial has been agitated vigorously, or the solution has been exposed to direct sunlight

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In RV failure/shock, some basic tenets including treating reversible causes, optimizing preload and afterload, and using inotropes and/or temporary MCS for as limited time as possible