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The benefits last only as long as the medication is used, and high costs make long-term treatment unrealistic for many
HFD intake increases the proportion of lipopolysaccharide-containing gut microbiota, triggering metabolic endotoxemia, a low-grade inflammation factor [158]
Some patients prefer this approach to ease into treatment and minimize side effects while still supporting steady weight loss under medical supervision
This is particularly dangerous for elderly people who already have a reduced appetite and may exacerbate muscle loss [65]
Additionally, enrichment related to obesity and pathways associated with multiple CVDs phenotypes, such as coronary artery disease and hypertension, were observed
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