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Kidney stones
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Once blood levels reach steady state through daily dosing, the long half-life of semaglutide (approximately 7 days) means levels do not drop dramatically between doses
Most people report feeling significantly better by week 2 and have their eating routine dialed in by week 4
Non-obese individuals often seek these medications for improved body composition, reduced visceral fat accumulation, better glycemic control, or cardiovascular risk factor modification
doi: 10.1016/S0140-6736(19)31150-X 98 PratleyRETuttleKRRossingPRasmussenSPerkovicVNielsenOWet al
