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After 82 wk of treatment of T2DM patients with exenatide, the placebo-subtracted weight loss from baseline is approximately 5% [886]

Nausea, vomiting, and diarrhea are particularly common when starting treatment or during dose increases, but these symptoms typically improve over time for most patients

This is a non-negotiable contraindication based on the boxed warning

Tirzepatide can affect hormonal balance in ways that indirectly influence bladder function

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