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A third incretin-based approach is tirzepatide, a dual agonist of GLP-1R and glucose-dependent insulinotropic polypeptide receptor (GIPR), which achieves greater HbA1c reduction and weight loss compared with GLP-1RAs alone

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Is Tirzepatide an effective solution for significant medical weight loss

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Aliment Pharmacol Ther 2008;27:186196

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