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Description
some randomized controlled trials demonstrated that liraglutide, dulaglutide, semaglutide, and albiglutide reduced the rate of CV events in T2DM patients ( Another novel glucose-lowering agent is tirzepatide which has a dual mechanism of action: a GLP-1 and a glucose-dependent insulinotropic polypeptide (GIP) co-agonist
The 0.25mg starting dose causes minimal gastric emptying changes
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Triple Receptor Binding Profile Glucose-Dependent Insulinotropic Polypeptide Agonism : The structural core of the molecule heavily favors GIP receptor affinity
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