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Drug Discov Today

However, the relationship with intestinal NE and GLP-1 has not been clarified

Pre-existing gastrointestinal disorders, particularly functional dyspepsia or irritable bowel syndrome, appear to predispose patients to more pronounced GI symptoms

Pharma giant Novo Nordisk is partnering with telehealth companies to expand access to its blockbuster weight loss drug Wegovy

S5 show that GLP-1RA were associated with lower risks as compared with placebo (16% lower risk), DPP-4 inhibitors (15% lower risk) and SGLT-2 inhibitors (10% lower risk), but the difference was statistically significant as compared with placebo only

Wegovy is FDA-approved for obesity and for cardiovascular risk reduction