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In the STEP2 research, nearly 1200 obese T2D were given 1 mg, 2.4 mg, or a placebo monthly

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They did however comment in their New England Journal of Medicine article that the affinity of lixisenatide for the GLP-1 receptor was up to four times greater than that of human GLP-1and there have been neuroprotective actions shown in animal models of Alzheimers disease. Together, I suspect these were likely strong rationales driving their choice of the use of Lixisenatide

The body produces antimicrobial substances such as bile and mucus, as well as has specialised immune cells in the intestinal wall

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